{"id":4045,"date":"2023-02-10T04:45:34","date_gmt":"2023-02-10T04:45:34","guid":{"rendered":"https:\/\/aucometoi.com\/?p=4045"},"modified":"2023-02-06T04:52:57","modified_gmt":"2023-02-06T04:52:57","slug":"thalassemia-can-benh-thieu-mau-o-tre-nhung-thua-sat-bam-sinh-o-nguoi-lon-so-luoc-ve-benh-va-cach-dieu-tri","status":"publish","type":"post","link":"https:\/\/aucometoi.com\/en\/thalassemia-can-benh-thieu-mau-o-tre-nhung-thua-sat-bam-sinh-o-nguoi-lon-so-luoc-ve-benh-va-cach-dieu-tri\/","title":{"rendered":"Thalassemia – c\u0103n b\u1ec7nh thi\u1ebfu m\u00e1u \u1edf tr\u1ebb nh\u01b0ng th\u1eeba s\u1eaft b\u1ea9m sinh \u1edf ng\u01b0\u1eddi l\u1edbn: S\u01a1 l\u01b0\u1ee3c v\u1ec1 b\u1ec7nh v\u00e0 c\u00e1ch \u0111i\u1ec1u tr\u1ecb"},"content":{"rendered":"

Thalassemia l\u00e0 g\u00ec?<\/h3>\n

Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng. N\u00f3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi m\u1ed9t \u0111\u1ed9t bi\u1ebfn trong gen t\u1ea1o ra beta-globin. Thalassemia l\u00e0 m\u1ed9t trong nh\u1eefng r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c \u0110\u1ecba Trung H\u1ea3i, nh\u01b0ng n\u00f3 c\u0169ng c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c ch\u00e2u Phi, ch\u00e2u \u00c1 ho\u1eb7c ng\u01b0\u1eddi M\u1ef9 b\u1ea3n \u0111\u1ecba.<\/p>\n

Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng. N\u00f3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi m\u1ed9t \u0111\u1ed9t bi\u1ebfn trong gen t\u1ea1o ra beta-globin. Thalassemia l\u00e0 m\u1ed9t trong nh\u1eefng r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c \u0110\u1ecba Trung H\u1ea3i, nh\u01b0ng n\u00f3 c\u0169ng c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c ch\u00e2u Phi, ch\u00e2u \u00c1 ho\u1eb7c ng\u01b0\u1eddi M\u1ef9 b\u1ea3n \u0111\u1ecba.<\/p>\n

Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng v\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c di truy\u1ec1n t\u1eeb cha m\u1eb9 ho\u1eb7c \u00f4ng b\u00e0. N\u00f3 g\u00e2y ra b\u1edfi \u0111\u1ed9t bi\u1ebfn gen t\u1ea1o ra beta-globin v\u00e0 g\u00e2y thi\u1ebfu m\u00e1u v\u00e0 t\u0103ng nguy c\u01a1 nhi\u1ec5m tr\u00f9ng do l\u01b0\u1ee3ng t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u th\u1ea5p.<\/p>\n

\"Thalassemia
Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng v\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c di truy\u1ec1n t\u1eeb cha m\u1eb9 ho\u1eb7c \u00f4ng b\u00e0.<\/figcaption><\/figure>\n

Nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u \u1edf thai nhi v\u00e0 t\u00ecnh tr\u1ea1ng qu\u00e1 t\u1ea3i s\u1eaft m\u00e3n t\u00ednh<\/h3>\n

Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1ch t\u1ea1o ra c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u. Khi m\u1ed9t ng\u01b0\u1eddi m\u1eafc b\u1ec7nh thalassemia, c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a h\u1ecd kh\u00f4ng th\u1ec3 v\u1eadn chuy\u1ec3n oxy \u0111\u00fang c\u00e1ch. Th\u1eeba s\u1eaft l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n kh\u00e1c x\u1ea3y ra khi c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u s\u1eaft v\u00e0 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn ch\u1ee9ng s\u1ee9c kh\u1ecfe nghi\u00eam tr\u1ecdng.<\/p>\n

B\u1ec7nh thalassemia v\u00e0 t\u00ecnh tr\u1ea1ng th\u1eeba s\u1eaft m\u00e3n t\u00ednh l\u00e0 hai t\u00ecnh tr\u1ea1ng li\u00ean quan \u0111\u1ebfn s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng erythropoietin (EPO). EPO k\u00edch th\u00edch s\u1ea3n xu\u1ea5t c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u m\u1edbi trong t\u1ee7y x\u01b0\u01a1ng v\u00e0 gi\u00fap c\u01a1 th\u1ec3 duy tr\u00ec m\u1ee9c \u0111\u1ed9 s\u1eaft.<\/p>\n

Vi\u1ec7c s\u1eed d\u1ee5ng nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a thai nhi trong nghi\u00ean c\u1ee9u \u0111\u00e3 d\u1eabn \u0111\u1ebfn nhi\u1ec1u b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 trong vi\u1ec7c t\u00ecm hi\u1ec3u c\u0103n b\u1ec7nh n\u00e0y, nh\u01b0ng ng\u01b0\u1eddi ta v\u1eabn ch\u01b0a ho\u00e0n to\u00e0n hi\u1ec3u \u0111\u01b0\u1ee3c nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u n\u00e0y ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o ho\u1eb7c t\u00e1c d\u1ee5ng c\u1ee7a ch\u00fang khi ti\u1ebfp x\u00fac v\u1edbi c\u00e1c t\u1ebf b\u00e0o kh\u00e1c.<\/p>\n

\u2014<\/p>\n

Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1.<\/h5>\n

R\u1ed1i lo\u1ea1n n\u00e0y c\u00f3 th\u1ec3 do s\u1ed1 l\u01b0\u1ee3ng nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a thai nhi b\u1ea5t th\u01b0\u1eddng. C\u00e0ng c\u00f3 nhi\u1ec1u nguy\u00ean h\u1ed3ng c\u1ea7u th\u00ec c\u00e0ng c\u00f3 nhi\u1ec1u kh\u1ea3 n\u0103ng b\u1ecb qu\u00e1 t\u1ea3i s\u1eaft m\u00e3n t\u00ednh.<\/p>\n

R\u1ed1i lo\u1ea1n \u0111i\u1ec1u h\u00f2a s\u1eaft v\u00e0 th\u1eeba s\u1eaft l\u00e0 hai t\u00ecnh tr\u1ea1ng c\u00f3 th\u1ec3 g\u00e2y ra b\u1ec7nh thalassemia. T\u00ecnh tr\u1ea1ng qu\u00e1 t\u1ea3i s\u1eaft x\u1ea3y ra khi c\u00f3 qu\u00e1 nhi\u1ec1u ch\u1ea5t s\u1eaft trong c\u01a1 th\u1ec3 v\u00e0 \u0111i\u1ec1u n\u00e0y g\u00e2y t\u1ed5n th\u01b0\u01a1ng cho c\u00e1c m\u00f4 v\u00e0 c\u01a1 quan, trong khi r\u1ed1i lo\u1ea1n \u0111i\u1ec1u h\u00f2a s\u1eaft x\u1ea3y ra khi kh\u00f4ng c\u00f3 \u0111\u1ee7 ch\u1ea5t s\u1eaft trong c\u01a1 th\u1ec3 v\u00e0 \u0111i\u1ec1u n\u00e0y g\u00e2y ra thi\u1ebfu m\u00e1u.<\/p>\n

C\u00e1c tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a b\u1ec7nh thalassemia l\u00e0 d\u1ec5 m\u1ec7t m\u1ecfi, xanh xao, kh\u00f3 th\u1edf, da nh\u1ee3t nh\u1ea1t do thi\u1ebfu m\u00e1u, n\u1ed3ng \u0111\u1ed9 huy\u1ebft s\u1eafc t\u1ed1 th\u1ea5p v\u00e0 s\u1ed1 l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u th\u1ea5p (thi\u1ebfu m\u00e1u).<\/p>\n

\u0110i\u1ec1u tr\u1ecb Thalassemia & Th\u1eeba s\u1eaft m\u00e3n t\u00ednh<\/h3>\n

Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1. N\u00f3 c\u00f3 th\u1ec3 g\u00e2y thi\u1ebfu m\u00e1u, m\u1ec7t m\u1ecfi v\u00e0 th\u1eadm ch\u00ed t\u1eed vong n\u1ebfu kh\u00f4ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u0111\u00fang c\u00e1ch. Thalassemia l\u00e0 do \u0111\u1ed9t bi\u1ebfn \u1edf m\u1ed9t trong nh\u1eefng gen s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u. N\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kho\u1ea3ng 1 tr\u00ean 2.000 ng\u01b0\u1eddi tr\u00ean to\u00e0n th\u1ebf gi\u1edbi v\u00e0 c\u00f3 th\u1ec3 truy\u1ec1n t\u1eeb cha m\u1eb9 sang con c\u00e1i.<\/p>\n

Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Thalassemia bao g\u1ed3m truy\u1ec1n m\u00e1u, l\u1ecdc m\u00e1u ho\u1eb7c li\u1ec7u ph\u00e1p th\u1ea3i s\u1eaft \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 t\u0103ng kh\u1ea3 n\u0103ng v\u1eadn chuy\u1ec3n oxy c\u1ee7a m\u00e1u v\u00e0 lo\u1ea1i b\u1ecf l\u01b0\u1ee3ng s\u1eaft d\u01b0 th\u1eeba ra kh\u1ecfi c\u01a1 th\u1ec3.<\/p>\n

Ngo\u00e0i c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y, c\u00f2n c\u00f3 c\u00e1c x\u00e9t nghi\u1ec7m di truy\u1ec1n c\u00f3 th\u1ec3 x\u00e1c \u0111\u1ecbnh li\u1ec7u m\u1ed9t ng\u01b0\u1eddi c\u00f3 b\u1ecb Thalassemia hay kh\u00f4ng tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/p>\n

\u2014<\/p>\n

Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n g\u00e2y ra s\u1ef1 c\u1ed1 c\u1ee7a c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u.<\/h5>\n

N\u00f3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a hai gen \u0111\u1ed9t bi\u1ebfn, m\u1ed9t gen t\u1eeb b\u1ed1 v\u00e0 m\u1eb9.<\/p>\n

Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh thalassemia l\u00e0 truy\u1ec1n m\u00e1u v\u00e0 b\u1ed5 sung s\u1eaft. L\u1ecdc m\u00e1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng n\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng t\u1ed1t v\u1edbi truy\u1ec1n m\u00e1u v\u00e0 b\u1ed5 sung s\u1eaft. Li\u1ec7u ph\u00e1p th\u1ea3i s\u1eaft c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb thay th\u1ebf khi qu\u00e1 tr\u00ecnh l\u1ecdc m\u00e1u th\u1ea5t b\u1ea1i ho\u1eb7c n\u1ebfu b\u1ec7nh nh\u00e2n \u0111ang ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o trong h\u01a1n 3 th\u00e1ng.<\/p>\n

Ch\u00fang ta s\u1ebd th\u1ea3o lu\u1eadn v\u1ec1 c\u00e1ch th\u1ee9c ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a ch\u00fang trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh thalassemia v\u00e0 t\u00ecnh tr\u1ea1ng th\u1eeba s\u1eaft m\u00e3n t\u00ednh.<\/p>\n

\u2014<\/p>\n

Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n tan m\u00e1u b\u1ea9m sinh, trong \u0111\u00f3 c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u c\u00f3 l\u01b0\u1ee3ng huy\u1ebft s\u1eafc t\u1ed1 th\u1ea5p b\u1ea5t th\u01b0\u1eddng, khi\u1ebfn c\u01a1 th\u1ec3 ph\u00e2n h\u1ee7y qu\u00e1 nhi\u1ec1u ch\u1ea5t s\u1eaft.<\/h3>\n

Thalassemia l\u00e0 m\u1ed9t c\u0103n b\u1ec7nh suy nh\u01b0\u1ee3c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u1ea3 tr\u1ebb em v\u00e0 ng\u01b0\u1eddi l\u1edbn. \u0110i\u1ec1u tr\u1ecb t\u1ed1n k\u00e9m v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n s\u1edbm \u0111\u1ec3 c\u00f3 k\u1ebft qu\u1ea3 t\u1ed1t nh\u1ea5t c\u00f3 th\u1ec3.<\/p>\n

Theo c\u00e1c b\u00e1c s\u0129, tr\u1ebb thi\u1ebfu m\u00e1u nh\u01b0ng th\u1eeba s\u1eaft c\u00f3 th\u1ec3 do b\u1ec7nh Thalassemia. B\u1ec7nh n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n qua x\u00e9t nghi\u1ec7m m\u00e1u ho\u1eb7c qua c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 xanh xao, l\u1eeb \u0111\u1eeb, ch\u1eadm l\u1edbn.<\/p>\n

\u2014<\/p>\n

Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 trong b\u1ec7nh thi\u1ebfu m\u00e1u.<\/h5>\n

B\u1ec7nh n\u00e0y c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh tan m\u00e1u b\u1ea9m sinh.<\/p>\n

Theo c\u00e1c b\u00e1c s\u0129, tr\u1ebb b\u1ecb thi\u1ebfu m\u00e1u nh\u01b0ng th\u1eeba s\u1eaft c\u00f3 th\u1ec3 do b\u1ec7nh Thalassemia (tan m\u00e1u b\u1ea9m sinh). B\u1ec7nh n\u00e0y \u0111i\u1ec1u tr\u1ecb t\u1ed1n k\u00e9m v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n s\u1edbm. N\u00f3 c\u00f3 th\u1ec3 g\u00e2y t\u1ed5n th\u01b0\u01a1ng cho c\u00e1c c\u01a1 quan n\u1ed9i t\u1ea1ng, \u0111\u1eb7c bi\u1ec7t l\u00e0 tim v\u00e0 n\u00e3o.<\/p>\n

Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 trong b\u1ec7nh thi\u1ebfu m\u00e1u. B\u1ec7nh n\u00e0y c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh tan m\u00e1u b\u1ea9m sinh.<\/p>\n

\u2014<\/p>\n

Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft l\u00e0 t\u00ecnh tr\u1ea1ng c\u01a1 th\u1ec3 c\u00f3 l\u01b0\u1ee3ng s\u1eaft th\u1ea5p h\u01a1n b\u00ecnh th\u01b0\u1eddng.<\/h3>\n

N\u00f3 th\u01b0\u1eddng g\u1eb7p nh\u1ea5t \u1edf tr\u1ebb em v\u00e0 th\u01b0\u1eddng do thi\u1ebfu m\u00e1u t\u00e1n huy\u1ebft g\u00e2y ra.<\/p>\n

Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n ph\u1ed5 bi\u1ebfn \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u1ea3 ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em. N\u00f3 c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 m\u1ec7t m\u1ecfi, suy nh\u01b0\u1ee3c, kh\u00f3 th\u1edf, ch\u00f3ng m\u1eb7t, da nh\u1ee3t nh\u1ea1t v\u00e0 l\u01b0\u1ee1i nh\u1ee3t nh\u1ea1t.<\/p>\n

\u2014<\/p>\n

Thi\u1ebfu m\u00e1u thi\u1ebfu s\u1eaft l\u00e0 t\u00ecnh tr\u1ea1ng c\u01a1 th\u1ec3 kh\u00f4ng c\u00f3 \u0111\u1ee7 ch\u1ea5t s\u1eaft.<\/h5>\n

\u0110i\u1ec1u n\u00e0y d\u1eabn \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 huy\u1ebft s\u1eafc t\u1ed1 th\u1ea5p, l\u00e0 t\u1ebf b\u00e0o v\u1eadn chuy\u1ec3n oxy trong m\u00e1u.<\/p>\n

Thalassemia l\u00e0 m\u1ed9t ch\u1ee9ng r\u1ed1i lo\u1ea1n di truy\u1ec1n x\u1ea3y ra khi c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t l\u01b0\u1ee3ng huy\u1ebft s\u1eafc t\u1ed1 b\u1ea5t th\u01b0\u1eddng, c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft.<\/p>\n

Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft kh\u00f4ng ph\u1ea3i l\u00e0 t\u00ecnh tr\u1ea1ng nghi\u00eam tr\u1ecdng v\u00e0 th\u01b0\u1eddng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng l\u00e2u d\u00e0i \u0111\u1ebfn s\u1ee9c kh\u1ecfe. Tuy nhi\u00ean, n\u00f3 c\u00f3 th\u1ec3 nguy hi\u1ec3m \u0111\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh thalassemia v\u00ec n\u00f3 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe k\u00e9m nh\u01b0 m\u1ec7t m\u1ecfi v\u00e0 b\u1ec7nh tim.<\/p>\n

\u2014<\/p>\n

Thi\u1ebfu m\u00e1u thi\u1ebfu s\u1eaft l\u00e0 t\u00ecnh tr\u1ea1ng m\u00e1u kh\u00f4ng \u0111\u1ee7 s\u1eaft.<\/h5>\n

\u0110\u00e2y l\u00e0 m\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n ph\u1ed5 bi\u1ebfn nh\u1ea5t g\u00e2y thi\u1ebfu m\u00e1u \u1edf tr\u1ebb em.<\/p>\n

Thi\u1ebfu m\u00e1u thi\u1ebfu s\u1eaft x\u1ea3y ra khi thi\u1ebfu ch\u1ea5t s\u1eaft trong c\u01a1 th\u1ec3. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 x\u1ea3y ra do \u0103n kh\u00f4ng \u0111\u1ee7, t\u0103ng m\u1ea5t ho\u1eb7c gi\u1ea3m h\u1ea5p thu t\u1eeb ru\u1ed9t. Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft c\u00f3 th\u1ec3 c\u00f3 nhi\u1ec1u nguy\u00ean nh\u00e2n v\u00e0 tri\u1ec7u ch\u1ee9ng bao g\u1ed3m:<\/p>\n

    \n
  • – H\u1ee5t h\u01a1i<\/li>\n
  • – C\u1ea3m th\u1ea5y m\u1ec7t<\/li>\n
  • – M\u00e0u da nh\u1ee3t nh\u1ea1t<\/li>\n
  • – Kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng t\u1eadp trung<\/li>\n
  • – Ch\u00e1n \u0103n ho\u1eb7c t\u0103ng c\u00e2n k\u00e9m<\/li>\n<\/ul>\n

    \u2014<\/p>\n

    Thalassemia l\u00e0 b\u1ec7nh r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n g\u00e2y thi\u1ebfu m\u00e1u.<\/h3>\n

    N\u00f3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a hai gen \u0111\u1ed9t bi\u1ebfn \u0111\u01b0\u1ee3c th\u1eeba h\u01b0\u1edfng t\u1eeb c\u1ea3 b\u1ed1 v\u00e0 m\u1eb9.<\/p>\n

    Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00fd nghi\u00eam tr\u1ecdng trong c\u01a1 th\u1ec3. \u0110\u00e2y l\u00e0 l\u00fac l\u01b0\u1ee3ng s\u1eaft trong c\u01a1 th\u1ec3 v\u01b0\u1ee3t qu\u00e1 m\u1ee9c c\u1ea7n thi\u1ebft. Ru\u1ed9t, c\u01a1 b\u1eafp c\u0169ng b\u1ecb \u1ea3nh h\u01b0\u1edfng do kh\u00f4ng th\u1ec3 h\u1ea5p th\u1ee5 \u0111\u1ee7 oxy v\u00e0 ch\u1ea5t dinh d\u01b0\u1ee1ng t\u1eeb m\u00e1u, d\u1eabn \u0111\u1ebfn y\u1ebfu c\u01a1 v\u00e0 gi\u1ea3m kh\u1ea3 n\u0103ng v\u1eadn \u0111\u1ed9ng.<\/p>\n

    Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng ch\u1ea5t b\u1ed5 sung s\u1eaft ho\u1eb7c truy\u1ec1n m\u00e1u, nh\u01b0ng c\u00f3 th\u1ec3 kh\u00f4ng ch\u1eefa \u0111\u01b0\u1ee3c \u0111\u1ed1i v\u1edbi m\u1ed9t s\u1ed1 ng\u01b0\u1eddi do c\u00e1c t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe kh\u00e1c nh\u01b0 b\u1ec7nh thalassemia ho\u1eb7c b\u1ec7nh hemochromatosis.<\/p>\n

    \u2014<\/p>\n

    Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft l\u00e0 t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00fd x\u1ea3y ra khi c\u01a1 th\u1ec3 c\u00f3 l\u01b0\u1ee3ng s\u1eaft th\u1ea5p.<\/h5>\n

    N\u00f3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi m\u1ed9t s\u1ed1 y\u1ebfu t\u1ed1, bao g\u1ed3m r\u1ed1i lo\u1ea1n di truy\u1ec1n, kinh nguy\u1ec7t nhi\u1ec1u v\u00e0 b\u1ec7nh celiac.<\/p>\n

    Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n g\u00e2y ra t\u00ecnh tr\u1ea1ng n\u00e0y. Trong ch\u1ee9ng r\u1ed1i lo\u1ea1n n\u00e0y, c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u huy\u1ebft s\u1eafc t\u1ed1 trong m\u00e1u khi\u1ebfn c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u kh\u00f3 v\u1eadn chuy\u1ec3n oxy \u0111i kh\u1eafp c\u01a1 th\u1ec3. Ng\u01b0\u1eddi \u0111\u00f3 s\u1ebd b\u1ecb thi\u1ebfu m\u00e1u v\u00e0 c\u00f3 th\u1ec3 b\u1ecb suy nh\u01b0\u1ee3c ho\u1eb7c m\u1ec7t m\u1ecfi v\u00ec h\u1ecd kh\u00f4ng nh\u1eadn \u0111\u1ee7 oxy cho t\u1ebf b\u00e0o.<\/p>\n

    Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft c\u0169ng c\u00f3 th\u1ec3 do kinh nguy\u1ec7t ra nhi\u1ec1u ho\u1eb7c b\u1ec7nh celiac khi\u1ebfn ru\u1ed9t b\u1ecb vi\u00eam nhi\u1ec1u v\u00e0 h\u1ec7 ti\u00eau h\u00f3a kh\u00f4ng h\u1ea5p th\u1ee5 ch\u1ea5t dinh d\u01b0\u1ee1ng \u0111\u00fang c\u00e1ch.<\/p>\n

    \u2014<\/p>\n

    Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft l\u00e0 t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00fd trong \u0111\u00f3 l\u01b0\u1ee3ng s\u1eaft trong c\u01a1 th\u1ec3 qu\u00e1 th\u1ea5p.<\/h5>\n

    \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 do thi\u1ebfu ch\u1ea5t s\u1eaft, m\u1ea5t m\u00e1u ho\u1eb7c c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 s\u1ea3n xu\u1ea5t h\u1ed3ng c\u1ea7u.<\/p>\n

    Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft l\u00e0 m\u1ed9t trong nh\u1eefng d\u1ea1ng thi\u1ebfu m\u00e1u ph\u1ed5 bi\u1ebfn nh\u1ea5t v\u00e0 n\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u1ea3 tr\u1ebb em v\u00e0 ng\u01b0\u1eddi l\u1edbn. Nh\u1eefng ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 m\u1eafc t\u00ecnh tr\u1ea1ng n\u00e0y bao g\u1ed3m nh\u1eefng ng\u01b0\u1eddi \u0111\u00e3 ph\u1eabu thu\u1eadt d\u1ea1 d\u00e0y ho\u1eb7c c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a kh\u00e1c, nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh th\u1eadn m\u00e3n t\u00ednh, nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh celiac v\u00e0 ph\u1ee5 n\u1eef \u0111ang mang thai ho\u1eb7c \u0111ang cho con b\u00fa. Trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p, m\u1ecdi ng\u01b0\u1eddi c\u00f3 th\u1ec3 kh\u00f4ng bi\u1ebft m\u00ecnh b\u1ecb thi\u1ebfu s\u1eaft v\u00ec c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ecd c\u00f3 th\u1ec3 m\u01a1 h\u1ed3.<\/p>\n

    C\u00e1c v\u1eadn \u0111\u1ed9ng vi\u00ean n\u00ean \u0111\u1eb7c bi\u1ec7t c\u1ea9n th\u1eadn v\u1ec1 t\u00ecnh tr\u1ea1ng n\u00e0y v\u00ec h\u1ecd c\u00f3 xu h\u01b0\u1edbng m\u1ea5t m\u1ed9t l\u01b0\u1ee3ng m\u00e1u l\u1edbn trong qu\u00e1 tr\u00ecnh t\u1eadp luy\u1ec7n v\u00e0 thi \u0111\u1ea5u do t\u0103ng kh\u1ed1i l\u01b0\u1ee3ng c\u01a1 v\u00e0 tan m\u00e1u do t\u1eadp luy\u1ec7n.<\/p>\n

    \u2014<\/p>\n

    Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n khi\u1ebfn c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u t\u1ebf b\u00e0o m\u00e1u mang oxy.<\/h3>\n

    T\u00ecnh tr\u1ea1ng n\u00e0y c\u00f3 th\u1ec3 g\u00e2y thi\u1ebfu m\u00e1u, thi\u1ebfu c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u trong c\u01a1 th\u1ec3.<\/p>\n

    Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n khi\u1ebfn c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u t\u1ebf b\u00e0o m\u00e1u mang oxy. T\u00ecnh tr\u1ea1ng n\u00e0y c\u00f3 th\u1ec3 g\u00e2y thi\u1ebfu m\u00e1u, thi\u1ebfu c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u trong c\u01a1 th\u1ec3. Thalassemia c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n b\u1eb1ng c\u00e1ch ki\u1ec3m tra n\u1ed3ng \u0111\u1ed9 hemoglobin b\u1ea5t th\u01b0\u1eddng v\u00e0 n\u1ed3ng \u0111\u1ed9 hematocrit th\u1ea5p v\u00e0 c\u1ea7n \u0111i\u1ec1u tr\u1ecb b\u1eb1ng truy\u1ec1n m\u00e1u c\u00f3 ch\u1ee9a s\u1eaft ho\u1eb7c ti\u00eam erythropoietin.<\/p>\n

    Thalassemia c\u0169ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a s\u1ee9c kh\u1ecfe nh\u01b0 tim, gan v\u00e0 x\u01b0\u01a1ng. C\u00e1c tri\u1ec7u ch\u1ee9ng bao g\u1ed3m m\u1ec7t m\u1ecfi, kh\u00f3 th\u1edf, da nh\u1ee3t nh\u1ea1t, ch\u00f3ng m\u1eb7t v\u00e0 ch\u1ea3y m\u00e1u qu\u00e1 nhi\u1ec1u do v\u1ebft c\u1eaft ho\u1eb7c v\u1ebft tr\u1ea7y x\u01b0\u1edbc.<\/p>\n

    \u2014<\/p>\n

    Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n g\u00e2y thi\u1ebfu m\u00e1u.<\/h5>\n

    N\u00f3 th\u01b0\u1eddng b\u1ecb ch\u1ea9n \u0111o\u00e1n nh\u1ea7m l\u00e0 thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft.<\/p>\n

    D\u1ea5u hi\u1ec7u \u0111\u1ea7u ti\u00ean c\u1ee7a b\u1ec7nh Thalassemia th\u01b0\u1eddng l\u00e0 s\u1ed1 l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u (RBC) th\u1ea5p h\u01a1n b\u00ecnh th\u01b0\u1eddng. D\u1ea5u hi\u1ec7u th\u1ee9 hai l\u00e0 n\u1ed3ng \u0111\u1ed9 huy\u1ebft s\u1eafc t\u1ed1 th\u1ea5p, nguy\u00ean nh\u00e2n l\u00e0 do gi\u1ea3m s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u.<\/p>\n

    Thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n d\u1ec5 d\u00e0ng b\u1eb1ng x\u00e9t nghi\u1ec7m m\u00e1u \u0111\u01a1n gi\u1ea3n, nh\u01b0ng Thalassemia ch\u1ec9 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c x\u00e1c nh\u1eadn b\u1eb1ng sinh thi\u1ebft t\u1ee7y x\u01b0\u01a1ng ho\u1eb7c x\u00e9t nghi\u1ec7m di truy\u1ec1n.<\/p>\n

    \u2014<\/p>\n

    Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n x\u1ea3y ra khi c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u ho\u1eb7c qu\u00e1 \u00edt m\u1ed9t lo\u1ea1i huy\u1ebft s\u1eafc t\u1ed1 nh\u1ea5t \u0111\u1ecbnh.<\/h5>\n

    Th\u00f4ng th\u01b0\u1eddng nh\u1ea5t, c\u00f3 s\u1ef1 thi\u1ebfu h\u1ee5t trong vi\u1ec7c s\u1ea3n xu\u1ea5t alpha-globin, l\u00e0m cho c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u d\u1ec5 v\u1ee1 h\u01a1n v\u00e0 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn thi\u1ebfu m\u00e1u.<\/p>\n

    Tr\u1ebb em \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc b\u1ec7nh thalassemia c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n b\u1ed5 sung s\u1eaft \u0111\u1ec3 gi\u00fap ng\u0103n ng\u1eeba b\u1ec7nh thi\u1ebfu m\u00e1u. Tuy nhi\u00ean, l\u01b0\u1ee3ng s\u1eaft d\u01b0 th\u1eeba c\u00f3 th\u1ec3 g\u00e2y ra v\u1ea5n \u0111\u1ec1 cho tr\u1ebb em m\u1eafc b\u1ec7nh thalassemia c\u0169ng nh\u01b0 ng\u01b0\u1eddi l\u1edbn.<\/p>\n

    C\u00e1c d\u1ea5u hi\u1ec7u thi\u1ebfu m\u00e1u \u1edf tr\u1ebb em c\u00f3 th\u1ec3 bao g\u1ed3m: m\u1ec7t m\u1ecfi, da nh\u1ee3t nh\u1ea1t, \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t.<\/p>\n

    \u2014<\/p>\n

    Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1ch c\u01a1 th\u1ec3 s\u1eed d\u1ee5ng s\u1eaft.<\/h3>\n

    N\u1ebfu kh\u00f4ng c\u00f3 \u0111\u1ee7 ch\u1ea5t s\u1eaft, c\u01a1 th\u1ec3 kh\u00f4ng th\u1ec3 s\u1ea3n xu\u1ea5t \u0111\u1ee7 huy\u1ebft s\u1eafc t\u1ed1, l\u00e0 m\u1ed9t lo\u1ea1i protein trong c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u. \u0110i\u1ec1u n\u00e0y d\u1eabn \u0111\u1ebfn thi\u1ebfu m\u00e1u v\u00e0 c\u00e1c v\u1ea5n \u0111\u1ec1 s\u1ee9c kh\u1ecfe kh\u00e1c.<\/p>\n

    L\u01b0\u1ee3ng s\u1eaft trong c\u01a1 th\u1ec3 con ng\u01b0\u1eddi l\u00e0 c\u00f3 h\u1ea1n, n\u1ebfu d\u01b0 th\u1eeba c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn ch\u1ee9ng nh\u01b0 s\u1ee5t c\u00e2n, suy dinh d\u01b0\u1ee1ng, th\u1ea5p c\u00f2i v\u00e0 thi\u1ebfu m\u00e1u. \u0110i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ee5 n\u1eef mang thai ph\u1ea3i bi\u1ebft v\u1ec1 t\u00ecnh tr\u1ea1ng n\u00e0y \u0111\u1ec3 h\u1ecd c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba c\u1ea7n thi\u1ebft cho s\u1ee9c kh\u1ecfe c\u1ee7a em b\u00e9.<\/p>\n

    Thalassemia l\u00e0 do \u0111\u1ed9t bi\u1ebfn gen g\u1ecdi l\u00e0 gen HBB tr\u00ean nhi\u1ec5m s\u1eafc th\u1ec3 11.<\/p>","protected":false},"excerpt":{"rendered":"

    Thalassemia l\u00e0 g\u00ec? Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng. N\u00f3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi m\u1ed9t \u0111\u1ed9t bi\u1ebfn trong gen t\u1ea1o ra beta-globin. Thalassemia l\u00e0 m\u1ed9t trong nh\u1eefng r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c \u0110\u1ecba Trung H\u1ea3i, nh\u01b0ng n\u00f3 c\u0169ng c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c ch\u00e2u Phi, ch\u00e2u \u00c1 ho\u1eb7c ng\u01b0\u1eddi M\u1ef9 b\u1ea3n \u0111\u1ecba. Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng. N\u00f3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi m\u1ed9t \u0111\u1ed9t bi\u1ebfn trong gen t\u1ea1o ra beta-globin. Thalassemia l\u00e0 m\u1ed9t trong nh\u1eefng r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c \u0110\u1ecba Trung H\u1ea3i, nh\u01b0ng n\u00f3 c\u0169ng c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ngu\u1ed3n g\u1ed1c ch\u00e2u Phi, ch\u00e2u \u00c1 ho\u1eb7c ng\u01b0\u1eddi M\u1ef9 b\u1ea3n \u0111\u1ecba. Thalassemia l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng v\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c di truy\u1ec1n t\u1eeb cha m\u1eb9 ho\u1eb7c \u00f4ng b\u00e0. N\u00f3 g\u00e2y ra b\u1edfi \u0111\u1ed9t bi\u1ebfn gen t\u1ea1o ra beta-globin v\u00e0 g\u00e2y thi\u1ebfu m\u00e1u v\u00e0 t\u0103ng nguy c\u01a1 nhi\u1ec5m tr\u00f9ng do l\u01b0\u1ee3ng t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u th\u1ea5p. Nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u \u1edf thai nhi v\u00e0 t\u00ecnh tr\u1ea1ng qu\u00e1 t\u1ea3i s\u1eaft m\u00e3n t\u00ednh Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1ch t\u1ea1o ra c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u. Khi m\u1ed9t ng\u01b0\u1eddi m\u1eafc b\u1ec7nh thalassemia, c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a h\u1ecd kh\u00f4ng th\u1ec3 v\u1eadn chuy\u1ec3n oxy \u0111\u00fang c\u00e1ch. Th\u1eeba s\u1eaft l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n kh\u00e1c x\u1ea3y ra khi c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t qu\u00e1 nhi\u1ec1u s\u1eaft v\u00e0 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn ch\u1ee9ng s\u1ee9c kh\u1ecfe nghi\u00eam tr\u1ecdng. B\u1ec7nh thalassemia v\u00e0 t\u00ecnh tr\u1ea1ng th\u1eeba s\u1eaft m\u00e3n t\u00ednh l\u00e0 hai t\u00ecnh tr\u1ea1ng li\u00ean quan \u0111\u1ebfn s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng erythropoietin (EPO). EPO k\u00edch th\u00edch s\u1ea3n xu\u1ea5t c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u m\u1edbi trong t\u1ee7y x\u01b0\u01a1ng v\u00e0 gi\u00fap c\u01a1 th\u1ec3 duy tr\u00ec m\u1ee9c \u0111\u1ed9 s\u1eaft. Vi\u1ec7c s\u1eed d\u1ee5ng nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a thai nhi trong nghi\u00ean c\u1ee9u \u0111\u00e3 d\u1eabn \u0111\u1ebfn nhi\u1ec1u b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 trong vi\u1ec7c t\u00ecm hi\u1ec3u c\u0103n b\u1ec7nh n\u00e0y, nh\u01b0ng ng\u01b0\u1eddi ta v\u1eabn ch\u01b0a ho\u00e0n to\u00e0n hi\u1ec3u \u0111\u01b0\u1ee3c nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u n\u00e0y ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o ho\u1eb7c t\u00e1c d\u1ee5ng c\u1ee7a ch\u00fang khi ti\u1ebfp x\u00fac v\u1edbi c\u00e1c t\u1ebf b\u00e0o kh\u00e1c. \u2014 Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1. R\u1ed1i lo\u1ea1n n\u00e0y c\u00f3 th\u1ec3 do s\u1ed1 l\u01b0\u1ee3ng nguy\u00ean b\u00e0o h\u1ed3ng c\u1ea7u c\u1ee7a thai nhi b\u1ea5t th\u01b0\u1eddng. C\u00e0ng c\u00f3 nhi\u1ec1u nguy\u00ean h\u1ed3ng c\u1ea7u th\u00ec c\u00e0ng c\u00f3 nhi\u1ec1u kh\u1ea3 n\u0103ng b\u1ecb qu\u00e1 t\u1ea3i s\u1eaft m\u00e3n t\u00ednh. R\u1ed1i lo\u1ea1n \u0111i\u1ec1u h\u00f2a s\u1eaft v\u00e0 th\u1eeba s\u1eaft l\u00e0 hai t\u00ecnh tr\u1ea1ng c\u00f3 th\u1ec3 g\u00e2y ra b\u1ec7nh thalassemia. T\u00ecnh tr\u1ea1ng qu\u00e1 t\u1ea3i s\u1eaft x\u1ea3y ra khi c\u00f3 qu\u00e1 nhi\u1ec1u ch\u1ea5t s\u1eaft trong c\u01a1 th\u1ec3 v\u00e0 \u0111i\u1ec1u n\u00e0y g\u00e2y t\u1ed5n th\u01b0\u01a1ng cho c\u00e1c m\u00f4 v\u00e0 c\u01a1 quan, trong khi r\u1ed1i lo\u1ea1n \u0111i\u1ec1u h\u00f2a s\u1eaft x\u1ea3y ra khi kh\u00f4ng c\u00f3 \u0111\u1ee7 ch\u1ea5t s\u1eaft trong c\u01a1 th\u1ec3 v\u00e0 \u0111i\u1ec1u n\u00e0y g\u00e2y ra thi\u1ebfu m\u00e1u. C\u00e1c tri\u1ec7u ch\u1ee9ng ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a b\u1ec7nh thalassemia l\u00e0 d\u1ec5 m\u1ec7t m\u1ecfi, xanh xao, kh\u00f3 th\u1edf, da nh\u1ee3t nh\u1ea1t do thi\u1ebfu m\u00e1u, n\u1ed3ng \u0111\u1ed9 huy\u1ebft s\u1eafc t\u1ed1 th\u1ea5p v\u00e0 s\u1ed1 l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u th\u1ea5p (thi\u1ebfu m\u00e1u). \u0110i\u1ec1u tr\u1ecb Thalassemia & Th\u1eeba s\u1eaft m\u00e3n t\u00ednh Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1. N\u00f3 c\u00f3 th\u1ec3 g\u00e2y thi\u1ebfu m\u00e1u, m\u1ec7t m\u1ecfi v\u00e0 th\u1eadm ch\u00ed t\u1eed vong n\u1ebfu kh\u00f4ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u0111\u00fang c\u00e1ch. Thalassemia l\u00e0 do \u0111\u1ed9t bi\u1ebfn \u1edf m\u1ed9t trong nh\u1eefng gen s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u. N\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kho\u1ea3ng 1 tr\u00ean 2.000 ng\u01b0\u1eddi tr\u00ean to\u00e0n th\u1ebf gi\u1edbi v\u00e0 c\u00f3 th\u1ec3 truy\u1ec1n t\u1eeb cha m\u1eb9 sang con c\u00e1i. Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Thalassemia bao g\u1ed3m truy\u1ec1n m\u00e1u, l\u1ecdc m\u00e1u ho\u1eb7c li\u1ec7u ph\u00e1p th\u1ea3i s\u1eaft \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 t\u0103ng kh\u1ea3 n\u0103ng v\u1eadn chuy\u1ec3n oxy c\u1ee7a m\u00e1u v\u00e0 lo\u1ea1i b\u1ecf l\u01b0\u1ee3ng s\u1eaft d\u01b0 th\u1eeba ra kh\u1ecfi c\u01a1 th\u1ec3. Ngo\u00e0i c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y, c\u00f2n c\u00f3 c\u00e1c x\u00e9t nghi\u1ec7m di truy\u1ec1n c\u00f3 th\u1ec3 x\u00e1c \u0111\u1ecbnh li\u1ec7u m\u1ed9t ng\u01b0\u1eddi c\u00f3 b\u1ecb Thalassemia hay kh\u00f4ng tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb. \u2014 Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n g\u00e2y ra s\u1ef1 c\u1ed1 c\u1ee7a c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u. N\u00f3 \u0111\u01b0\u1ee3c g\u00e2y ra b\u1edfi s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a hai gen \u0111\u1ed9t bi\u1ebfn, m\u1ed9t gen t\u1eeb b\u1ed1 v\u00e0 m\u1eb9. Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh thalassemia l\u00e0 truy\u1ec1n m\u00e1u v\u00e0 b\u1ed5 sung s\u1eaft. L\u1ecdc m\u00e1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng n\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng t\u1ed1t v\u1edbi truy\u1ec1n m\u00e1u v\u00e0 b\u1ed5 sung s\u1eaft. Li\u1ec7u ph\u00e1p th\u1ea3i s\u1eaft c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb thay th\u1ebf khi qu\u00e1 tr\u00ecnh l\u1ecdc m\u00e1u th\u1ea5t b\u1ea1i ho\u1eb7c n\u1ebfu b\u1ec7nh nh\u00e2n \u0111ang ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o trong h\u01a1n 3 th\u00e1ng. Ch\u00fang ta s\u1ebd th\u1ea3o lu\u1eadn v\u1ec1 c\u00e1ch th\u1ee9c ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a ch\u00fang trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh thalassemia v\u00e0 t\u00ecnh tr\u1ea1ng th\u1eeba s\u1eaft m\u00e3n t\u00ednh. \u2014 Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n tan m\u00e1u b\u1ea9m sinh, trong \u0111\u00f3 c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u c\u00f3 l\u01b0\u1ee3ng huy\u1ebft s\u1eafc t\u1ed1 th\u1ea5p b\u1ea5t th\u01b0\u1eddng, khi\u1ebfn c\u01a1 th\u1ec3 ph\u00e2n h\u1ee7y qu\u00e1 nhi\u1ec1u ch\u1ea5t s\u1eaft. Thalassemia l\u00e0 m\u1ed9t c\u0103n b\u1ec7nh suy nh\u01b0\u1ee3c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u1ea3 tr\u1ebb em v\u00e0 ng\u01b0\u1eddi l\u1edbn. \u0110i\u1ec1u tr\u1ecb t\u1ed1n k\u00e9m v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n s\u1edbm \u0111\u1ec3 c\u00f3 k\u1ebft qu\u1ea3 t\u1ed1t nh\u1ea5t c\u00f3 th\u1ec3. Theo c\u00e1c b\u00e1c s\u0129, tr\u1ebb thi\u1ebfu m\u00e1u nh\u01b0ng th\u1eeba s\u1eaft c\u00f3 th\u1ec3 do b\u1ec7nh Thalassemia. B\u1ec7nh n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n qua x\u00e9t nghi\u1ec7m m\u00e1u ho\u1eb7c qua c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 xanh xao, l\u1eeb \u0111\u1eeb, ch\u1eadm l\u1edbn. \u2014 Thalassemia l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n m\u00e1u di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c s\u1ea3n xu\u1ea5t huy\u1ebft s\u1eafc t\u1ed1 trong b\u1ec7nh thi\u1ebfu m\u00e1u. B\u1ec7nh n\u00e0y c\u00f2n \u0111\u01b0\u1ee3c<\/p>","protected":false},"author":3,"featured_media":4047,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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